Absorption of lipids

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Effects of Lipids on Absorption of Poorly Water-Soluble Drugs

Introduction Although the capability of ingested lipids to enhance the bioavailability of poorly water-soluble drugs has been experimentally observed and established 1 , the phenomenon is not well understood and is unpredictable. Commercially, lipids could offer valuable opportunities for enabling oral drug delivery, as approximately 4070% of all new drug candidates have been estimated to have ...

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Digestion and absorption of lipids in the ruminant.

Clary, J. J., Mitchell, G. E. Jr & Little, C . 0. (1967). J. Anim. Sci. 26, 917. Clegg, K. M. (1956). J. Sci. Fd Agric. 7 , 40. Elsden, S. R., Hitchcock, M. W. S., Marshall, H. A. & Phillipson, A. T. (1945-6). J. exp. Biol. 22, 191. Gray, F. V. (1947). 3. exp. Biol. 24, 15. Hale, E. B., Duncan, C. W. & Huffman, C. I;. (1947). J . Nutr. 34, 241. Hassid, W. Z. & Neufeld, F. (1964). In Methods in ...

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Structured lipids improve fat absorption in normal and malabsorbing rats.

The presence of medium-chain fatty acids in dietary fatty acid as well as the triacylglycerol structure may influence the absorption and lymphatic transport of fatty acids. We compared the lymphatic transport and recovery of fatty acids from four intragastrically administered fats based on rapeseed oil and decanoic acid in two rat models of normal absorption and malabsorption, respectively. The...

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Digestion and absorption of lipids by sheep fed chopped and ground dried grass.

Three wether sheep equipped with re-entrant cannulae at the proximal duodenum and terminal ileum were given dried cocksfoot in the chopped or ground form and the samples of duodenal and ilea! digesta and faeces obtained for both diets were analysed for individual long-chain fatty acids. The total quantities of fatty acids entering the proximal duodenum (15.2 and 15.4 g/24 h on chopped and groun...

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Methamphetamine absorption by skin lipids: accumulated mass, partition coefficients, and the influence of fatty acids.

Occupants of former methamphetamine laboratories, often residences, may experience increased exposure through the accumulation of the methamphetamine in the organic films that coat skin and indoor surfaces. The objectives of this study were to determine equilibrium partition coefficients of vapor-phase methamphetamine with artificial sebum (AS-1), artificial sebum without fatty acids (AS-2), an...

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ژورنال

عنوان ژورنال: Biochemical Journal

سال: 1972

ISSN: 0306-3283

DOI: 10.1042/bj1280008pb